Details - CureSickleCell

Study ID	1030
Name	Adult Sickle Cell Quality of Life Measurement Information System Field Test
Contact Email	sankeller@air.org
Acronym	ASCQ-Me
Period	2016
Design	Field Test
Study PI	San Keller
Institution	American Institutes of Research
URL	https://dataverse.harvard.edu/dataset.xhtml?persistentId=doi:10.7910/DVN/8OFSL3
CTGovID	NA
Funding Agency	NHLBI
Grant Number	HHSN-268-2005-74264C

Overview	ASCQ-MeSM (Adult Sickle Cell Quality of Life Measurement Information System) is a patient-reported outcome measurement system that evaluates and monitors the physical, mental, and social well-being of adults with sickle cell disease. Measure development began with a comprehensive literature review that identified important aspects of HRQOL for assessment including pain and its management, emotional distress, functioning in social, family, sexual, and work-related roles, overall quality of life, and quality of care. Field testing of items was conducted with 556 adults recruited through seven geographically diverse US clinics.
Focus Areas	1. Pain 2. Emotional distress 3. Social-role functioning 4. Overall quality of life 5. Quality of care
Outcomes	1. Pain Impact 2. Emotional Impact 3. Sleep Quality 4. Social Functioning 5. Physical Functioning

Data Location	Harvard Dataverse
Biospecimen Available	N/A
Data Consent	Harvard Dataverse
Biospecimen Consent	No sample
Contact Consent	NA
Genomic Data	No

Age Range	18-64
No. Participants	561
Inclusion Criteria	1. Had a confirmed diagnosis of sickle cell disease (SCD). 2. Were 18 years of age or older. 3. Were able to provide informed consent. 4. Did not have significant cognitive impairments that would interfere with their ability to complete the survey.
Exclusion Criteria	1. Did not have a confirmed diagnosis of sickle cell disease (SCD). 2. Were under the age of 18. 3. Were unable to provide informed consent. 4. Had a significant cognitive impairment that would interfere with their ability to complete the survey.

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Clinical status (76)

Behavior (1)

Concept	Variables
Substance Use	Comrbd12

Blood (2)

Concept	Variables
Acute Anemic Episode
Aplastic Crisis
Bleeding
Other Blood Problem
Sickle Cell Disease	Q195_Severity2A_3 SC_Type

Cancer (1)

Concept	Variables
Cancer	Comrbd10

Cardiovascular (2)

Concept	Variables
Aneurysm
Cardiac Failure
Cardiovascular Problem	Comrbd1
Heart Problem	Comrbd4

Digestive (1)

Concept	Variables
Gastrointestinal Problem
Hepatitis	Comrbd2
Liver Problem

Endocrine (1)

Concept	Variables
Diabetes Mellitus	Comrbd9
Endocrine Problem

Family MedHx (0)

General Health (0)

Genitourinary (3)

Concept	Variables
Genitourinary Problem
Kidney Problem	SevYN_4
Priapism	SexFxM1 SexFxM1_rc
Renal Dialysis History

Immune (1)

Concept	Variables
Fever
HIV Infection	Comrbd13
Immune Problem
Infection
Vaccination

Lymphatic (0)

Medical Event (0)

Medical History (0)

Mental Health (32)

Concept	Variables
Anxiety
Depression
Emotional Health	B3_1_P_11 B3_1_P_17 B3_1_P_7 B3_2_A_1 B3_2_A_2 B3_2_A_3 B3_2_A_4 B3_2_A_5 B3_2_A_6 B3_2_A_7 B3_2_A_8 B3_2_A_9 B3_2_D_1 B3_2_D_10 B3_2_D_11 B3_2_D_12 B3_2_D_13 B3_2_D_14 B3_2_D_15 B3_2_D_16 B3_2_D_17 B3_2_D_18 B3_2_D_19 B3_2_D_2 B3_2_D_3 B3_2_D_4 B3_2_D_5 B3_2_D_6 B3_2_D_7 B3_2_D_8 B3_2_D_9
Mental status
Psychiatric Disorder	Comrbd11

Musculoskeletal (2)

Concept	Variables
Musculoskeletal Problem
Osteomyelitis
Osteonecrosis	SevYN_6
Rheumatic Diseases	Comrbd5

Neurodevelopmental (0)

Neurologic (1)

Concept	Variables
Meningitis
Neurologic Event
Seizure
Stroke	SevYN_7
Transient Ischemic Attack

Nutritional and Metabolic (0)

Ocular (1)

Concept	Variables
Ocular Problem
Sickle Retinopathy	SevYN_5

Oral (0)

Pain (0)

Reproductive (1)

Concept	Variables
Birth Outcome
Gestational Age
Menstruation
Pregnancy	Comrbd3
Reproductive Behavior

Respiratory (4)

Concept	Variables
Acute Chest Syndrome	SevYN_2
Asthma	Comrbd7
Lung Disease	Comrbd8 SevYN_3
Other Respiratory Problem

Skin (1)

Concept	Variables
Skin Problem	SevYN_1

Sleep (20)

Concept	Variables
Sleep Problem	B3_1_Sl_1 B3_1_Sl_10 B3_1_Sl_11 B3_1_Sl_12 B3_1_Sl_13 B3_1_Sl_14 B3_1_Sl_15 B3_1_Sl_16 B3_1_Sl_17 B3_1_sl_18 B3_1_Sl_19 B3_1_Sl_2 B3_1_Sl_20 B3_1_Sl_3 B3_1_Sl_4 B3_1_Sl_5 B3_1_Sl_6 B3_1_Sl_7 B3_1_Sl_8 B3_1_Sl_9

Surgery History (2)

Concept	Variables
Cardiovascular
Digestive	SevYN_9
Genitourinary
Lymphatic	SevYN_8
Musculoskeletal
Ocular
Respiratory
Surgery History

COVID-19 (0)

Diagnosis (0)

Impact (0)

Treatment (0)

Vaccination (0)

Demographics (2)

Concept	Variables
Address
Age	Age
Ethnic Group
Gender	Sex
Language
National Origin
Nuclear Family
Race

Social Determinants of Health (SDoH) (0)

Socioeconomic Status (0)

Environmental Exposure (0)

Exposure (0)

Health Care (26)

Acute Care Utilization (14)

Concept	Variables
Facility Type
Provider Type
Quality of Care	QOCEm Access2 BadEm EmBleve EmComm1 EmComm2 EmComm3 EmHlp_pain EmWait DlayCare
Visit	NoVisPr Screen1 Screen3 Times_Em_pain

Health Services (0)

Healthcare utilization (12)

Concept	Variables
Country of Care
Facility Type
Quality of Care	QOCAll QOCAppt QOCDr DrComm1 DrComm2 DrComm3 DrComm4 DrKnow DrSCDSp HIns Screen2 Access1

Hospitalization (0)

SCD Management (0)

Imaging (0)

Angiogram (0)

Catheterization (0)

CT Scan (0)

Echocardiogram (0)

Electrocardiogram (ECG) (0)

Electrodiagnosis (0)

General Imaging (0)

MRI/MRA (0)

Nuclear Medicine Imaging (0)

PET scan (0)

Transcranial Doppler (TCD) (0)

Ultrasound (0)

X-Ray (0)

Parent/Caretaker (0)

Demographics (0)

Psychosocial (0)

Quality of Life (0)

Quality of Life (183)

Functional Status (124)

Concept	Variables
Behavior	SexFx1 SexFx2 SexFx3 SexFx4 SexFx4_rc SexFx5 SexFx5_rc SexFx6 SexFx7 SexFx8 SexFxM2 SexFxM3
Cognitive	B3_4_A_1 B3_4_A_2 B3_4_A_3 B3_4_A_4 B3_4_A_5 B3_4_E_1 B3_4_E_2 B3_4_E_3 B3_4_E_4 B3_4_E_5 B3_4_E_6 B3_4_E_7 B3_4_M_1 B3_4_M_2 B3_4_M_3 B3_4_M_4 B3_4_M_5 B3_4_M_6 B3_4_V_1 B3_4_V_10 B3_4_V_2 B3_4_V_3 B3_4_V_4 B3_4_V_5 B3_4_V_6 B3_4_V_7 B3_4_V_8 B3_4_V_9
Mental Health	Global10 Global4 PROMIS SF-Anger 1_ItmCnt PROMIS SF-Anger 1_RawScore PROMIS SF-Anger 1_SE PROMIS SF-Anger 1_TScore PROMIS SF-Anxiety 1_ItmCnt PROMIS SF-Anxiety 1_RawScore PROMIS SF-Anxiety 1_SE PROMIS SF-Anxiety 1_TScore PROMIS SF-Depression 1_ItmCnt PROMIS SF-Depression 1_RawScore PROMIS SF-Depression 1_SE PROMIS SF-Depression 1_TScore
Physical	Global3 Global6 Global8 PROMIS Bank-Phys. Function 1_ItmCnt PROMIS Bank-Phys. Function 1_RawScore PROMIS Bank-Phys. Function 1_SE PROMIS Bank-Phys. Function 1_TScore PROMIS SF-Phys. Function 1_ItmCnt PROMIS SF-Phys. Function 1_RawScore PROMIS SF-Phys. Function 1_SE PROMIS SF-Phys. Function 1_TScore
SCD Management
Sleep/Fatigue	PROMIS Bank-Fatigue 1_ItmCnt PROMIS Bank-Fatigue 1_RawScore PROMIS Bank-Fatigue 1_SE PROMIS Bank-Fatigue 1_TScore PROMIS SF-Fatigue 1_ItmCnt PROMIS SF-Fatigue 1_RawScore PROMIS SF-Fatigue 1_SE PROMIS SF-Fatigue 1_TScore PROMIS SF-Sleep Disturb 1_ItmCnt PROMIS SF-Sleep Disturb 1_RawScore PROMIS SF-Sleep Disturb 1_SE PROMIS SF-Sleep Disturb 1_TScore PROMIS SF-Wake Disturb 1_ItmCnt PROMIS SF-Wake Disturb 1_RawScore PROMIS SF-Wake Disturb 1_SE PROMIS SF-Wake Disturb 1_TScore
Social	B3_3_B_1 B3_3_B_2 B3_3_B_3 B3_3_B_4 B3_3_B_5 B3_3_B_6 B3_3_B_7 B3_3_B_8 B3_3_B_9 B3_3_F_1 B3_3_F_10 B3_3_F_11 B3_3_F_12 B3_3_F_2 B3_3_F_3 B3_3_F_4 B3_3_F_5 B3_3_F_6 B3_3_F_7 B3_3_F_8 B3_3_F_9 B3_3_G_1 B3_3_G_2 B3_3_G_3 B3_3_G_4 B3_3_G_5 B3_3_G_6 B3_3_SS_1 B3_3_SS_2 B3_3_SS_3 B3_3_SS_4 B3_3_SS_5 B3_3_SS_6 Global5 Global9 PROMIS SF-Social Sat DSA 1_ItmCnt PROMIS SF-Social Sat DSA 1_RawScore PROMIS SF-Social Sat DSA 1_SE PROMIS SF-Social Sat DSA 1_TScore PROMIS SF-Social Sat Rol 1_ItmCnt PROMIS SF-Social Sat Rol 1_RawScore PROMIS SF-Social Sat Rol 1_SE PROMIS SF-Social Sat Rol 1_TScore

General Health (2)

Concept	Variables
General Health	Global1 Global2

Pain (57)

Concept	Variables
General Pain	B3_1_P_1 B3_1_P_10 B3_1_P_12 B3_1_P_13 B3_1_P_14 B3_1_P_15 B3_1_P_16 B3_1_P_2 B3_1_P_3 B3_1_P_8 B3_1_P_9 Comrbd6 Global7 PROMIS Bank-Pain Interference 1_ItmCnt PROMIS Bank-Pain Interference 1_RawScore PROMIS Bank-Pain Interference 1_SE PROMIS Bank-Pain Interference 1_TScore PROMIS SF-Pain Behavior 1_ItmCnt PROMIS SF-Pain Behavior 1_RawScore PROMIS SF-Pain Behavior 1_SE PROMIS SF-Pain Behavior 1_TScore PROMIS SF-Pain Interference 1_ItmCnt PROMIS SF-Pain Interference 1_RawScore PROMIS SF-Pain Interference 1_SE PROMIS SF-Pain Interference 1_TScore
Pain Attack	B3_1_P_5 SevPain1 SevPain1_rc SevPain2 SevPain3 SevPain4 SevPain5 SexFx9 SexFxF1 SexFxF2 Times_Mng_at_home
Skeletal and Joint Pain	B3_1_P_4 B3_1_P_6 B3_1_St_1 B3_1_St_10 B3_1_St_11 B3_1_St_12 B3_1_St_13 B3_1_St_14 B3_1_St_15 B3_1_St_16 B3_1_St_17 B3_1_St_18 B3_1_St_19 B3_1_St_2 B3_1_St_3 B3_1_St_4 B3_1_St_5 B3_1_St_6 B3_1_St_7 B3_1_St_8 B3_1_St_9

Tests (0)

Biopsy (0)

Blood (0)

Cardiovascular (0)

Genitourinary (0)

Immune (0)

Microbiology Culture (0)

Musculoskeletal (0)

Neurologic (0)

Ocular (0)

Other (0)

Physical Exam (0)

Reproductive (0)

Respiratory (0)

Therapeutics (3)

Medication (2)

Concept	Variables
Antibiotics
Asthma
Blood Medication History
Cardiovascular
Compliance
Current Medication
Depression Medication History
Hydroxyurea	SevYN_10
Medication
Neurologic Medication History
Pain	SevYN_12
SCD Medication
Sildenafil
Supplements

Surgery (0)

Transfusion (1)

Concept	Variables
Blood Transfusion	SevYN_11
Chronic Transfusion
Transfusion Complications

Transplantation (0)

Treatment (0)

Study Publications

Adult sickle cell quality-of-life measurement information system (ASCQ-Me): conceptual model based on review of the literature and formative research.

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Mental Health (89)

Concept	Variables
ASCQ-Me Emotional Impact	B3_2_A_1 B3_2_A_2 B3_2_A_3 B3_2_A_4 B3_2_A_5 B3_2_A_6 B3_2_A_7 B3_2_A_8 B3_2_A_9 B3_2_D_1 B3_2_D_10 B3_2_D_11 B3_2_D_12 B3_2_D_13 B3_2_D_14 B3_2_D_15 B3_2_D_16 B3_2_D_17 B3_2_D_18 B3_2_D_19 B3_2_D_2 B3_2_D_3 B3_2_D_4 B3_2_D_5 B3_2_D_6 B3_2_D_7 B3_2_D_8 B3_2_D_9
ASCQ-Me Social Functioning	B3_3_B_1 B3_3_B_2 B3_3_B_3 B3_3_B_4 B3_3_B_5 B3_3_B_6 B3_3_B_7 B3_3_B_8 B3_3_B_9 B3_3_F_1 B3_3_F_10 B3_3_F_11 B3_3_F_12 B3_3_F_2 B3_3_F_3 B3_3_F_4 B3_3_F_5 B3_3_F_6 B3_3_F_7 B3_3_F_8 B3_3_F_9 B3_3_G_1 B3_3_G_2 B3_3_G_3 B3_3_G_4 B3_3_G_5 B3_3_G_6 B3_3_SS_1 B3_3_SS_2 B3_3_SS_3 B3_3_SS_4 B3_3_SS_5 B3_3_SS_6
Brief Resiliency Scale
NeuroQOL Fatigue
NIH Toolbox Loneliness
Pearlin Enhanced Self-Efficacy Scale
Profile of Mood States (POMS)
PROMIS Anger	PROMIS SF-Anger 1_ItmCnt PROMIS SF-Anger 1_RawScore PROMIS SF-Anger 1_SE PROMIS SF-Anger 1_TScore
PROMIS Anxiety	PROMIS SF-Anxiety 1_ItmCnt PROMIS SF-Anxiety 1_RawScore PROMIS SF-Anxiety 1_SE PROMIS SF-Anxiety 1_TScore
PROMIS Depression	PROMIS SF-Depression 1_ItmCnt PROMIS SF-Depression 1_RawScore PROMIS SF-Depression 1_SE PROMIS SF-Depression 1_TScore
PROMIS Emotional Support
PROMIS Fatigue	PROMIS Bank-Fatigue 1_ItmCnt PROMIS Bank-Fatigue 1_RawScore PROMIS Bank-Fatigue 1_SE PROMIS Bank-Fatigue 1_TScore PROMIS SF-Fatigue 1_ItmCnt PROMIS SF-Fatigue 1_RawScore PROMIS SF-Fatigue 1_SE PROMIS SF-Fatigue 1_TScore
PROMIS Global Mental Health
PROMIS Satisfaction with Participation in Discretionary Social Activities	PROMIS SF-Social Sat DSA 1_ItmCnt PROMIS SF-Social Sat DSA 1_RawScore PROMIS SF-Social Sat DSA 1_SE PROMIS SF-Social Sat DSA 1_TScore PROMIS SF-Social Sat Rol 1_ItmCnt PROMIS SF-Social Sat Rol 1_RawScore PROMIS SF-Social Sat Rol 1_SE PROMIS SF-Social Sat Rol 1_TScore

Neurodevelopment (0)

Neuropsychological (28)

Concept	Variables
Adaptive Behavior Assessment System-II
Adverse Childhood Experience Questionnaire (ACE-Q)
Beery Developmental Test of Visual-Motor Integration
Benton Tactile Form Perception Test
Mini Mental Status Examination (MMSE)
Oral Verbal Fluency Test
PROMIS Cognitive Function	B3_4_A_1 B3_4_A_2 B3_4_A_3 B3_4_A_4 B3_4_A_5 B3_4_E_1 B3_4_E_2 B3_4_E_3 B3_4_E_4 B3_4_E_5 B3_4_E_6 B3_4_E_7 B3_4_M_1 B3_4_M_2 B3_4_M_3 B3_4_M_4 B3_4_M_5 B3_4_M_6 B3_4_V_1 B3_4_V_10 B3_4_V_2 B3_4_V_3 B3_4_V_4 B3_4_V_5 B3_4_V_6 B3_4_V_7 B3_4_V_8 B3_4_V_9
Purdue Pegboard (SPA version)
Test of Everyday Attention (TEA)
Vineland Adaptive Behavior Summary
Wechsler Intelligence Scales
Wechsler Memory Scale
Wisconsin Card Sorting Test
Woodcock-Johnson Revised, Tests of Achievement
Woodcock-Johnson, Revised, Tests of Cognitive Ability

Pain (55)

Concept	Variables
ASCQ-Me Pain Episode	SevPain1 SevPain1_rc SevPain2 SevPain3 SevPain4 SevPain5 Times_Mng_at_home
ASCQ-Me Pain Impact	B3_1_P_1 B3_1_P_10 B3_1_P_11 B3_1_P_12 B3_1_P_13 B3_1_P_14 B3_1_P_15 B3_1_P_16 B3_1_P_17 B3_1_P_2 B3_1_P_3 B3_1_P_4 B3_1_P_5 B3_1_P_6 B3_1_P_7 B3_1_P_8 B3_1_P_9
ASCQ-Me Stiffness Impact	B3_1_St_1 B3_1_St_10 B3_1_St_11 B3_1_St_12 B3_1_St_13 B3_1_St_14 B3_1_St_15 B3_1_St_16 B3_1_St_17 B3_1_St_18 B3_1_St_19 B3_1_St_2 B3_1_St_3 B3_1_St_4 B3_1_St_5 B3_1_St_6 B3_1_St_7 B3_1_St_8 B3_1_St_9
Brief Pain Inventory (BPI)
Chronic Pain
PROMIS Neuropathic Pain Quality
PROMIS Nociceptive Pain Quality
PROMIS Pain Behavior	PROMIS SF-Pain Behavior 1_ItmCnt PROMIS SF-Pain Behavior 1_RawScore PROMIS SF-Pain Behavior 1_SE PROMIS SF-Pain Behavior 1_TScore
PROMIS Pain Interference	PROMIS Bank-Pain Interference 1_ItmCnt PROMIS Bank-Pain Interference 1_RawScore PROMIS Bank-Pain Interference 1_SE PROMIS Bank-Pain Interference 1_TScore PROMIS SF-Pain Interference 1_ItmCnt PROMIS SF-Pain Interference 1_RawScore PROMIS SF-Pain Interference 1_SE PROMIS SF-Pain Interference 1_TScore

Physical Function (8)

Concept	Variables
6-Minute Walk Test
PROMIS Physical Functioning	PROMIS Bank-Phys. Function 1_ItmCnt PROMIS Bank-Phys. Function 1_RawScore PROMIS Bank-Phys. Function 1_SE PROMIS Bank-Phys. Function 1_TScore PROMIS SF-Phys. Function 1_ItmCnt PROMIS SF-Phys. Function 1_RawScore PROMIS SF-Phys. Function 1_SE PROMIS SF-Phys. Function 1_TScore
Tanner Stage

Psychosocial (0)

Quality of Care (26)

Concept	Variables
ASCQ-Me Healthcare Utilization	Access1 Access2 BadEm DlayCare DrComm1 DrComm2 DrComm3 DrComm4 DrKnow DrSCDSp EmBleve EmComm1 EmComm2 EmComm3 EmHlp_pain EmWait HIns NoVisPr QOCAll QOCAppt QOCDr QOCEm Screen1 Screen2 Screen3 Times_Em_pain
ASCQ-Me Quality of Care (QOC)
Patient Satisfaction Questionnaire (PSQ)

Quality of Life (53)

Concept	Variables
ASCQ-Me SCD Medical History Checklist	Comrbd1 Comrbd10 Comrbd11 Comrbd12 Comrbd13 Comrbd2 Comrbd3 Comrbd4 Comrbd5 Comrbd6 Comrbd7 Comrbd8 Comrbd9 Q195_Severity2A_3 SevYN_1 SevYN_10 SevYN_11 SevYN_12 SevYN_2 SevYN_3 SevYN_4 SevYN_5 SevYN_6 SevYN_7 SevYN_8 SevYN_9
ASCQ-Me Sexual Health	SexFx1 SexFx2 SexFx3 SexFx4 SexFx4_rc SexFx5 SexFx5_rc SexFx6 SexFx7 SexFx8 SexFx9 SexFxF1 SexFxF2 SexFxM1 SexFxM1_rc SexFxM2 SexFxM3
Child Health Questionnaire (CHQ)
Ladder of Life
Pediatric Quality of Life Inventory (PedsQL) (ages 1-12ms)
Pediatric Quality of Life Inventory (PedsQL) (ages 13-24ms)
Pediatric Quality of Life Inventory (PedsQL) (ages 2-4ys)
Pediatric Quality of Life Inventory (PedsQL) (ages 5-7)
Pediatric Quality of Life Inventory Child Report (ages 13-18)
Pediatric Quality of Life Inventory Child Report (ages 8-12)
Pediatric Quality of Life Inventory Parent Report for Child (ages 13-18)
Pediatric Quality of Life Inventory Parent Report for Child (ages 8-12)
PROMIS Global Health	Global1 Global10 Global2 Global3 Global4 Global5 Global6 Global7 Global8 Global9
PROMIS Global Physical Health
PROMIS Self-Efficacy for Managing Medications and Treatment
SF-36 Health Survey

Sleep (24)

Concept	Variables
ASCQ-Me Sleep Impact	B3_1_Sl_1 B3_1_Sl_10 B3_1_Sl_11 B3_1_Sl_12 B3_1_Sl_13 B3_1_Sl_14 B3_1_Sl_15 B3_1_Sl_16 B3_1_Sl_17 B3_1_sl_18 B3_1_Sl_19 B3_1_Sl_2 B3_1_Sl_20 B3_1_Sl_3 B3_1_Sl_4 B3_1_Sl_5 B3_1_Sl_6 B3_1_Sl_7 B3_1_Sl_8 B3_1_Sl_9
PROMIS Sleep Distrubance	PROMIS SF-Sleep Disturb 1_ItmCnt PROMIS SF-Sleep Disturb 1_RawScore PROMIS SF-Sleep Disturb 1_SE PROMIS SF-Sleep Disturb 1_TScore

Technology Support (0)

Study Documentation Select All	1. ASCQ-Me-Field-Test-ASCQ-Me-Data-Dictionary 2. ASCQ-Me-Field-Test-PROMIS-Scores-Data-Dictionary_v2
Forms Select All	1. ASCQ-Me Social Functioning Impact CAT 2. ASCQ-Me v2.0 - Emotional Impact CAT 3. ASCQ-Me v2.0 - Pain Impact CAT 4. ASCQ-Me v2.0 - Sleep Impact CAT 5. ASCQ-Me v2.0 - Stiffness Impact CAT 6. ASCQ-Me Pain Episode Frequency and Severity 7. ASCQ-Me SCD Medical History Checklist 8. ASCQ-Me Sexual Health 9. ASCQ-Me Healthcare Utilization 10. ASCQ-Me Healthcare Satisfaction 11. PROMIS Scale v1.2 - Global Health 12. PROMIS Fatigue 13. PROMIS Pain Interference 14. PROMIS Physical Functioning 15. PROMIS Anger 16. PROMIS Anxiety 17. PROMIS Depression 18. PROMIS Pain Behavior 19. PROMIS Sleep Distrubance 20. PROMIS Satisfaction with Participation in Discretionary Social Activities 21. PROMIS Cognitive Function v1.0

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